An efficient synthesis of 5-substituted 1H-tetrazoles using Zn/Al hydrotalcite catalyst
β Scribed by M. Lakshmi Kantam; K.B. Shiva Kumar; K. Phani Raja
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 116 KB
- Volume
- 247
- Category
- Article
- ISSN
- 1381-1169
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## Abstract The synthesis of 5βsubstituted 1β__H__βtetrazoles based on reaction of a series of aromatic nitriles with sodium azide was investigated. The reaction was catalyzed by modified montmorillonite Kβ10 including Cu^2+^, Fe^3+^, Ni^2+^, and Zn^2+^ metal ions. The best results obtained by Mont
Simple and Efficient Synthesis of 5-Substituted 1-H-Tetrazoles Using Metal-Modified Clay Catalysts. -Metal-modified montmorillonite K10 efficiently catalyzes the synthesis of tetrazoles (II) (10 examples) using click chemistry. The catalysts can be reused several times without significant loss of th