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An efficient synthesis of (2S,3R)-3-hydroxylysine via ruthenium catalyzed asymmetric hydrogenation

✍ Scribed by Estelle Coulon; Maria Cristina Caño de Andrade; Virginie Ratovelomanana-Vidal; Jean-Pierre Genêt


Publisher
Elsevier Science
Year
1998
Tongue
French
Weight
207 KB
Volume
39
Category
Article
ISSN
0040-4039

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✦ Synopsis


An efficient synthesis of the natural occuring amino acid (2S.3R)-3-hydroxylysine is reported. The five step sequence features a highly enantioselective dynamic kinetic resolution of racemic o~acetamido [J-keto phtidimidohexanoate using ruthenium(ll) catalyzed hydrogenation reaction.


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ChemInform Abstract: (1S,3R,4R)-2-Azanor
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