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An efficient synthesis of 2-trifluoromethyl quinolines via gold-catalyzed cyclization of trifluoromethylated propargylamines

✍ Scribed by Mei Zhu; Weijun Fu; Guanglong Zou; Chen Xun; Dongsheng Deng; Baoming Ji


Book ID
113711600
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
722 KB
Volume
135
Category
Article
ISSN
0022-1139

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Efficient Synthesis of 2-Fluoromethylate
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## Abstract 2‐Fluoromethylated quinolines were synthesized through the reaction of __N__‐aryl‐fluorinated imidoyl iodides with terminal alkynes in good yields by the catalysis of copper(I) iodide (CuI) alone.