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An efficient synthesis and biological testing of novel 3-chloro-4-aryl-1-(4-(phenyldiazenyl)phenyl)azetidin-2-ones

✍ Scribed by Himani N. Chopde; Ramakanth Pagadala; Jyotsna S. Meshram; Venkateshwarlu Jetti


Book ID
102344069
Publisher
Journal of Heterocyclic Chemistry
Year
2010
Tongue
English
Weight
96 KB
Volume
47
Category
Article
ISSN
0022-152X

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✦ Synopsis


Abstract

magnified image__N__‐Benzylidene‐4‐(phenyldiazenyl)aniline (Ia, Ib, Ic, Id, Ie, If, Ig, Ih, Ii, Ij) has been prepared from p‐aminoazobenzene with different aromatic aldehydes under microwave irradiation, which on further treatment with chloro acetic acid and POCl~3~ in the presence of triethyl amine gave the title compounds. The structure of the compounds has been confirmed by spectroscopic techniques (IR and ^1^H NMR) and elemental analysis. These azetidinones analogues were screened for their antimicrobial activities against strains of different microorganisms. Some of the compounds displayed the promising antibacterial activities against some bacterial strains. J. Heterocyclic Chem., (2010).


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