An efficient synthesis and biological testing of novel 3-chloro-4-aryl-1-(4-(phenyldiazenyl)phenyl)azetidin-2-ones
β Scribed by Himani N. Chopde; Ramakanth Pagadala; Jyotsna S. Meshram; Venkateshwarlu Jetti
- Book ID
- 102344069
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 2010
- Tongue
- English
- Weight
- 96 KB
- Volume
- 47
- Category
- Article
- ISSN
- 0022-152X
- DOI
- 10.1002/jhet.459
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β¦ Synopsis
Abstract
magnified image__N__βBenzylideneβ4β(phenyldiazenyl)aniline (Ia, Ib, Ic, Id, Ie, If, Ig, Ih, Ii, Ij) has been prepared from pβaminoazobenzene with different aromatic aldehydes under microwave irradiation, which on further treatment with chloro acetic acid and POCl~3~ in the presence of triethyl amine gave the title compounds. The structure of the compounds has been confirmed by spectroscopic techniques (IR and ^1^H NMR) and elemental analysis. These azetidinones analogues were screened for their antimicrobial activities against strains of different microorganisms. Some of the compounds displayed the promising antibacterial activities against some bacterial strains. J. Heterocyclic Chem., (2010).
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