An efficient stereoselective synthesis of Z-(2S)- and Z-(2R)-2-tert-butoxycarbonylamino-6-hydroxyhex-4-enoic acid, key intermediates in the synthesis of (2S,4S,5R)-(−)- and (2R,4R,5S)-(+)-bulgecinine

✍ Scribed by Karen E. Holt; Jonathan P. Swift; Mark E.B. Smith; Stephen J.C. Taylor; Raymond McCague

• Publisher: Elsevier Science
• Year: 2002
• Tongue: French
• Weight: 71 KB
• Volume: 43
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(01)02338-3

✦ Synopsis

An efficient stereoselective synthesis of Z-(2S)-and Z-(2R)-2-tert-butoxycarbonylamino

-6-hydroxyhex-4-enoic acid, key intermediates in the synthesis of (2S,4S,5R)-(-)-and (2R,4R,5S)-(+)-bulgecinine