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An efficient reduction of azides to amines: synthesis of DNA interactive pyrrolo[2,1-c][1,4]benzodiazepines

✍ Scribed by Ahmed Kamal; E Laxman; M Arifuddin

Publisher
Elsevier Science
Year
2000
Tongue
French
Weight
76 KB
Volume
41
Category
Article
ISSN
0040-4039

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Simple and facile reduction of azides to
Simple and facile reduction of azides to amines: synthesis of DNA interactive pyrrolo[2,1-c][1,4]benzodiazepines
✍ Ahmed Kamal; P.S.M.M. Reddy; D.Rajasekhar Reddy πŸ“‚ Article πŸ“… 2002 πŸ› Elsevier Science 🌐 French βš– 58 KB

The reduction of aromatic azido compounds to the corresponding amines with hydriodic acid has been investigated and found to result in high yields. This reductive methodology which proceeds under non refluxing condition has been extended for the synthesis of DNA-interactive pyrrolo[2,1-c][1,4] benzo

ChemInform Abstract: Simple and Facile R
ChemInform Abstract: Simple and Facile Reduction of Azides to Amines: Synthesis of DNA Interactive Pyrrolo[2,1-c][1,4]benzodiazepines.
✍ Ahmed Kamal; P. S. M. M. Reddy; D. Rajasekhar Reddy πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 31 KB πŸ‘ 2 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a β€œFull Text” option. The original article is trackable v

Efficient solid-phase synthesis of DNA-i
Efficient solid-phase synthesis of DNA-interactive pyrrolo[2,1-c][1,4]benzodiazepine antitumour antibiotics
✍ Ahmed Kamal; G.Suresh Kumar Reddy; K.Laxma Reddy; Sadagopan Raghavan πŸ“‚ Article πŸ“… 2002 πŸ› Elsevier Science 🌐 French βš– 83 KB

The solid-phase synthesis of DNA-interactive pyrrolo[2,1-c][1,4]benzodiazepine (PBD) imines and biologically important pyrrolo[2,1-c][1,4]benzodiazepine-5,11-diones on Wang resin using a reduction/cyclization procedure is reported.