## In the presence of palladium complexes and copper iodide. the reaction of propar& halides with terminal alkynes proceed rapidly to give conjugated allenynes in high yield. Propar& acetates and tosylates are also suited to the preparation of such allenes. The conjugated allenyne system has been
An Efficient palladium-catalysed reaction of vinyl and aryl halides or triflates with terminal alkynes
✍ Scribed by Mouaˆd Alami; Fabiola Ferri; Gérard Linstrumelle
- Publisher
- Elsevier Science
- Year
- 1993
- Tongue
- French
- Weight
- 258 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0040-4039
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📜 SIMILAR VOLUMES
The palladium(O)-catalysed coupling of aryl and vinyl triflates or halides with the easily available 2-ethynylaniline, followed by a palladium(IIl-catalysed cyclization step, provides an efficient and very versatile procedure for the synthesis of functionalyzed E-substituted indoles.
Coupling reaction of aryl and vinyl halides with terminal alkynes using a catalyst system of copper(I) iodide -triphenylphosphine proceeds efficiently in the presence of potassium carbonate to give the corresponding unsymmetrical acetylenes in good yield.