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An efficient one-step radiosynthesis of [18F]FE-PE2I, a PET radioligand for imaging of dopamine transporters

✍ Scribed by Vladimir Stepanov; Raisa Krasikova; Liina Raus; Olavi Loog; Jukka Hiltunen; Christer Halldin

Book ID
112132924
Publisher
John Wiley and Sons
Year
2012
Tongue
French
Weight
216 KB
Volume
55
Category
Article
ISSN
0022-2135

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One-step radiosynthesis of [18F]LBT-999:
One-step radiosynthesis of [18F]LBT-999: a selective radioligand for the visualization of the dopamine transporter with PET
✍ Frédéric Dollé; Julie Helfenbein; Françoise Hinnen; Sylvie Mavel; Zoïa Mincheva; 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 French ⚖ 153 KB

## Abstract LBT‐999 (8‐((__E__)‐4‐fluoro‐but‐2‐enyl)‐3‐beta‐__p__‐tolyl‐8‐aza‐bicyclo[3.2.1]octane‐2‐beta‐carboxylicacid methyl ester) is a recently developed cocaine derivative belonging to a new generation of highly selective dopamine transporter (DAT) ligands (__K__~D~: 9 nM for the DAT and IC~5