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An efficient one-pot three-component synthesis and antimicrobial evaluation of tetra substituted thiophene derivatives

✍ Scribed by Sable, Pravinkumar N.; Ganguly, Swastika; Chaudhari, Pravin D.

Book ID
121658830
Publisher
Chinese Electronic Periodical Services
Year
2014
Tongue
English
Weight
246 KB
Volume
25
Category
Article
ISSN
1001-8417

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This communication describes an efficient one-pot procedure for the synthesis of 2-arylbenzo[b]thiophene derivatives via reaction of o-halo or nitro aryl carbonyl compounds with benzyl mercaptans in the presence of an excess of anhydrous K 2 CO 3 at elevated temperature.