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An efficient method of generating transgenic mice by pronuclear microinjection

✍ Scribed by Richard Wing-Chuen Wong; Mai-Har Sham; Yu-Lung Lau; Siu-Yuen Chan


Book ID
111640122
Publisher
Humana Press Inc
Year
2000
Tongue
English
Weight
93 KB
Volume
15
Category
Article
ISSN
1073-6085

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## Abstract Transgenic and gene‐targeted mutant mice provide powerful tools for analysis of the cellular processes involved in early development and in the pathogenesis of many diseases. Here we describe a transgene integration strategy mediated by site‐specific recombination that allows establishm