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An efficient method for the synthesis of trifluoromethyl substituted heterocycles

✍ Scribed by Russell J. Linderman; Kirollos S. Kirollos

Publisher: Elsevier Science
Year: 1989
Tongue: French
Weight: 196 KB
Volume: 30
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(01)93708-6

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✦ Synopsis

Trifluoromethyl substituted pyrazoles and isoxazoles have been prepared regiospecifically in high yield from trifluoroacetyl acetylenes. The development of new and more efficient methods for the synthesis of trifluoromethyl substituted aromatic and heteroaromatic compounds are currently of considerable interest.l Agrochemicals such as Fluoemturon and Trifluralin, and pharmaceuticals such as Penfluridol

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