An efficient method for the synthesis of [4-15N]cytidine and [6-15N]adenosine derivatives from uridine and inosine
โ Scribed by Kazuo Kamaike; Mihoko Takahashi; Kazuyuki Utsugi; Kazue Tomizuka; Yoshiharu Ishido
- Book ID
- 103398641
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- French
- Weight
- 245 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
The conversion of 15N-enriched urea to a [1,3-15N2]cytidine derivative is accomplished in nine steps with an overall yield of 67%. Synthesis of a [4-15NH2]cytidine derivative is achieved by thiolation of the corresponding uridine derivative with Lawesson's reagent and amination with 15N-enriched amm
06-substituted guanosine and N3-substituted uridine derivatives were obtained in high yields by stannylation of the corresponding unsubstituted nucleosides with bis(tributy,ltin)oxide followed by treatment with various electrophiles.