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An efficient method for racemization free attachment of 9-fluorenylmethyloxycarbonyl-amino acids to peptide synthesis supports

✍ Scribed by Michael S. Bernatowicz; Thomas Kearney; Richard S. Neves; Hubert Köster

Publisher
Elsevier Science
Year
1989
Tongue
French
Weight
253 KB
Volume
30
Category
Article
ISSN
0040-4039

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✦ Synopsis

An efficient, general, and racemization free method of covalently attaching No-F'KKXZ protected amino acids to solid supports for peptide synthesis is described. The process involves the preparation of 2,4-dichlorophenyl-Na-Fmoc-aminoaql-4-oxyn~sthylphenoxy acetates which can be used to directly and efficiently acylate am&e furrctionalized polymers.

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