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An Efficient Method for Chlorination of Alcohols Using PPh3/Cl3CCONH2.

✍ Scribed by Wanchai Pluempanupat; Warinthorn Chavasiri


Publisher
John Wiley and Sons
Year
2006
Weight
22 KB
Volume
37
Category
Article
ISSN
0931-7597

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✦ Synopsis


Abstract

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A Mild and Efficient Method for Chlorina
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## Abstract A new and convenient stereoselective synthesis of (__Z__)‐2‐(chloromethyl)alk‐2‐enoates has been achieved from __Baylis–Hillman__ adducts by treatment with PPh~3~/Cl~3~CCONH~2~ at room temperature. The synthesis can proceed under mild and acid‐free conditions to form the products in hig