The first example of intermolecular carbon radical addition to unactivated aldoxime ethers in the preseace of BF3.OEt2 has provided a new efficient carbon-carbon bond-forming method for the synthesis of a variety of amines.
An efficient intermolecular carbon-carbon bond formation via SmI2-promoted anion radical alkylation
โ Scribed by Osamu Ujikawa; Junji Inanaga; Masaru Yamaguchi
- Book ID
- 104229290
- Publisher
- Elsevier Science
- Year
- 1989
- Tongue
- French
- Weight
- 273 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0040-4039
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o-Bromophenyl ally1 ether and N-ally1 o-bromoacetanilide reacted with tributyltin hydride in the presence of activated olefin compounds to give 2,3dihydrobenzofuran and 2,3-dihydroindole derivatives in modest yields via both intramolecular and intermolecular radical carbon-carbon bond formations. R