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Double carbon-carbon bond formations via both intramolecular and intermolecular radical reactions with tributyltin hydride to give 2, 3-dihydrobenzofuran and 2, 3-dihydroindole derivatives

✍ Scribed by Hideo Togo; Osamu Kikuchi


Publisher
Elsevier Science
Year
1988
Tongue
French
Weight
125 KB
Volume
29
Category
Article
ISSN
0040-4039

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✦ Synopsis


o-Bromophenyl ally1 ether and N-ally1 o-bromoacetanilide reacted with tributyltin hydride in the presence of activated olefin compounds to give 2,3dihydrobenzofuran and 2,3-dihydroindole derivatives in modest yields via both intramolecular and intermolecular radical carbon-carbon bond formations.

Recently, free radical mediated C-C bond forming reactions have been studied extensively. 1)

In those reactions, the reactions with tributyltin hydride are