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An efficient friedel-crafts synthesis of 2-acylbenzofurans

✍ Scribed by Melvyn Gill


Book ID
103401321
Publisher
Elsevier Science
Year
1984
Tongue
French
Weight
428 KB
Volume
40
Category
Article
ISSN
0040-4020

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A rapid and efficient synthesis of a new
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New pyrrolobenzodiazocines 3 have been prepared by an intramolecular Friedel-Crafts process from pyrrolobenzoacrylamides 2. The cyclisation process involving a 1,4-intramolecular addition of a pyrrole onto acrylamide led to the formation of an eight-membered ring.