Enzymatic kinetic resolution of (±)-4-ac
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Antonio Cipiciani; Francesco Fringuelli; Vittorio Mancini; Oriana Piermatti; Ann
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Article
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1997
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Elsevier Science
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French
⚖ 305 KB
The enzymatic kinetic resolution of (-+)-4-acetoxy122]paracyclophane by Candida cylindracea lipase was investigated in water and in a two-phase aqueous organic system. The (+)-(R)-4-hydroxy-and (+)-(S)-4-acetoxyl2,2l-paracyclophanes were isolated in excellent yields and high enantiomeric excesses. T