An efficient approach to N-protected 1,2,3,3a-tetrahydrocyclopenta[b]quinolin-1-ones

✍ Scribed by Martin Kratzel; Reza Mabhoti

• Book ID: 102339398
• Publisher: Journal of Heterocyclic Chemistry
• Year: 1998
• Tongue: English
• Weight: 353 KB
• Volume: 35
• Category: Article
• ISSN: 0022-152X
• DOI: 10.1002/jhet.5570350415

✦ Synopsis

Abstract

In the course of our investigations into the synthesis of benzoanalogues of streptazolin we also studied the construction of 1,2,3,3a‐tetrahydrocyclopenta[b]quinolin‐1‐ones which could be successfully solved by an intramolecular acylation using a bromo‐lithium exchange, starting from 3‐bromoquinoline.