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A general intramolecular Friedel–Crafts approach to functionalized pyrrolo[3,2,1-ij]quinolin-4-ones

✍ Scribed by Patil, Dadasaheb V.; Cavitt, Marchello A.; Grzybowski, Paul; France, Stefan


Book ID
119974380
Publisher
Royal Society of Chemistry
Year
2012
Tongue
English
Weight
762 KB
Volume
48
Category
Article
ISSN
1359-7345

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2,6-Dimethyl-9-methoxy-4H-pyrrolo [3,2,1
✍ F. Baccichetti; F. Carlassare; C. Marzano; A. Guiotto; P. Rodighiero; A. Chilin; 📂 Article 📅 1994 🏛 Elsevier Science 🌐 English ⚖ 869 KB

Some photobiological properties of 2,6-dimethyl-9-methoxy-4H-pyrrolo[3,2,1-ij]quinolin-4-one (PQ) have been studied in comparison with 8-methoxypsoralen (8-MOP). In Ehrlich cells, PQ induced a moderate inhibition in DNA and RNA syntheses in the dark, which appeared to be more pronounced upon UVA irr