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An efficient and regioselective iodination of electron-rich aromatic compounds using N-chlorosuccinimide and sodium iodide

✍ Scribed by Takuya Yamamoto; Kozo Toyota; Noboru Morita

Publisher: Elsevier Science
Year: 2010
Tongue: French
Weight: 683 KB
Volume: 51
Category: Article
ISSN: 0040-4039
DOI: 10.1016/j.tetlet.2009.12.125

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✦ Synopsis

An efficient and regioselective method for iodination of electron-rich aromatic compounds was found using N-chlorosuccinimide and sodium iodide in AcOH with short reaction times. This method is also applicable to non-benzenoid aromatic or heteroaromatic compounds.

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