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An efficient and modified biginelli one-pot synthesis of new isoxazole substitted 3,4-dihydropyrimidin-2(1H)-ones and thiones catalyzed by VCl3

โœ Scribed by E. Rajanarendar; P. Ramesh; G. Mohan; E. Kalyan Rao


Book ID
118284452
Publisher
Journal of Heterocyclic Chemistry
Year
2007
Tongue
English
Weight
235 KB
Volume
44
Category
Article
ISSN
0022-152X

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A one-pot Biginelli synthesis of 3,4-dih
โœ Abdelmadjid Debache; Mouna Amimour; Ali Belfaitah; Salah Rhouati; Bertrand Carbo ๐Ÿ“‚ Article ๐Ÿ“… 2008 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 163 KB

We report herein the use of triphenylphosphine (TPP) as a new catalyst for the one-pot Biginelli reaction coupling of b-ketoesters, aldehydes and urea (or thiourea) to afford the corresponding dihydropyrimidinones/thiones.