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An efficient and facile procedure for the synthesis of 4,6-diaryl-2(1H)-pyridones under solvent-free conditions

✍ Scribed by Liangce Rong; Haiying Wang; Jingwen Shi; Fang Yang; Hao Yao; Shuajiang Tu; Daqing Shi

Publisher
Journal of Heterocyclic Chemistry
Year
2007
Tongue
English
Weight
271 KB
Volume
44
Category
Article
ISSN
0022-152X

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✦ Synopsis

Abstract

magnified image

An efficient and convenient method for the preparation of 4,6‐diaryl‐2(1__H__)‐pyridones by the one‐pot reaction of aromatic aldehydes, aromatic ketones and malononitrile, in the presence of sodium hydroxide under solventfree condition is reported. This method has the advantages of good yields, mild reaction conditions, easy workup, inexpensive reagents and being environmentally friendly over the existing procedures.

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