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An efficient and facile one-pot synthesis of propargylamines by three-component coupling of aldehydes, amines, and alkynes via C–H activation catalyzed by NiCl2

✍ Scribed by Subhasis Samai; Ganesh Chandra Nandi; M.S. Singh

Book ID
104098222
Publisher
Elsevier Science
Year
2010
Tongue
French
Weight
352 KB
Volume
51
Category
Article
ISSN
0040-4039

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An efficient synthesis of propargylamine
An efficient synthesis of propargylamines via three-component coupling of aldehydes, amines and alkynes catalyzed by nanocrystalline copper(II) oxide
✍ M. Lakshmi Kantam; Soumi Laha; Jagjit Yadav; Suresh Bhargava 📂 Article 📅 2008 🏛 Elsevier Science 🌐 French ⚖ 112 KB

An efficient three-component coupling of aldehydes, amines and alkynes to prepare propargylamines, in nearly quantitative yields using nanocrystalline CuO as a catalyst is described. Structurally divergent aldehydes and amines were converted to the corresponding propargylamines. The reaction does no