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An Economical Large Scale Preparation of (2S,3S)-4,5-Dimethyl-2-Phenyl-L,3-Dioxolan

โœ Scribed by Kocienski, Philip; Street, Stephen D.A.


Book ID
111682940
Publisher
Taylor and Francis Group
Year
1984
Tongue
English
Weight
217 KB
Volume
14
Category
Article
ISSN
0039-7911

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An improved synthesis of (4S,5S)-2,2-dim
โœ Ivan C. Nordin; James A. Thomas ๐Ÿ“‚ Article ๐Ÿ“… 1984 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 99 KB

The title compound is prepared in 78% yield using an improved one-pot procedure which does not require final purification. The title compound (4S,5S)-2,2-dimethyl-4-phenyl-1,3-dioxan-5-amine ( 1) is an effective reagent for the synthesis of optically active amino acids (2)l and d-methyl amino acids