An easy synthesis of (RS)-[3?13C]mevalonic acid lactone
β Scribed by Scott, A. Ian; Shishido, Kozo
- Book ID
- 120252236
- Publisher
- The Royal Society of Chemistry
- Year
- 1980
- Tongue
- English
- Weight
- 147 KB
- Volume
- 9
- Category
- Article
- ISSN
- 0022-4936
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π SIMILAR VOLUMES
## Abstract The synthesis of (2,3β^13^C~2~) erucic acid, for use in metabolic studies, is reported. The synthesis employs a repeated 3 step reaction sequence using ^13^C labeled triethylphosphonoacetate to extend C~18:1~, oleyl alcohol, by 4 carbons. The starting alcohol is first oxidized with PCC
## Abstract [2β^13^C]βMonobromoacetic acid was prepared in good yield by the bromination of acetic acid in the presence of phosphorous trichloride by appropriate modification of the method of Marvel.(^1^) A byβproduct of this method was found to be bromoacetyl bromide, which could be avoided by hyd