An easy entry to isoquinoline alkaloids by aza-Wittig electrocyclic ring-closure
β Scribed by J Augusto; R Rodrigues; Genaro C Leiva; Joana D.F de Sousa
- Book ID
- 103398677
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- French
- Weight
- 153 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0040-4039
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π SIMILAR VOLUMES
A new method for the preparation of the pyrrolo[2,3-b]quinoline ring system involving the sequential formation of the pyridine ring (electrocyclic ring-closure) and the pyrrole (nitrene insertion reaction) rings. This approach is based on the regioselective formation of the iminophosphorane 2 from t
Aza Wittlg-type reactIonof~bu(rm~nophosphoranel I wrth one mole of-zsocyanate leads to the zmmophosphoranes 5 whrcti by treatment with a secondmok of-uocyanate affordedpyndo[2,3,Cde/qutnazo~nes 6 Smularly, reaction with ketenes leads to the formanon of benzo[del[l,6]naphthyrrdmes9 Direct converszon