✦ LIBER ✦
One pot preparation of pyrido[2,3,4-de]quinazolines and benzo[de][1,6]naphthyridines by a consecutive process involving an aza-Wittig/electrocyclic ring-closure/heterocumulene-mediated annelation or intramolecular Diels-Alder cycloaddition sequence.
✍ Scribed by Pedro Molina; Mateo Alajarín; Angel Vidal
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- French
- Weight
- 266 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
✦ Synopsis
Aza Wittlg-type reactIonof~bu(rm~nophosphoranel I wrth one mole of-zsocyanate leads to the zmmophosphoranes 5 whrcti by treatment with a secondmok of-uocyanate affordedpyndo[2,3,Cde/qutnazo~nes 6 Smularly, reaction with ketenes leads to the formanon of benzo[del[l,6]naphthyrrdmes9 Direct converszon I+6 and I -+9 were achteved usrng two moles of tsocyanate or ketene respectrvely