𝔖 Bobbio Scriptorium
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An E2F-like repressor of transcription

✍ Scribed by Morkel, M.; Wenkel, J.; Bannister, A. J.; Kouzarides, T.; Hagemeier, Christian

Book ID
109791914
Publisher
Nature Publishing Group
Year
1997
Tongue
English
Weight
221 KB
Volume
390
Category
Article
ISSN
0028-0836

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## Abstract Primarily, E2F factors such as E2F1, ‐2, and ‐3 stimulate cell‐cycle progression, while ARF tumor suppressor mediates growth suppression. The __ARF__ gene can be induced by oncogenic signal through activating E2F‐dependent transcription. In turn, ARF may target E2F for its degradation v