An efficient, practical asymmetric synthesis of (R)-norfluoxetine 1 and (R)-fluoxetine 2 has been achieved. The synthetic strategy features a Sharpless asymmetric dihydroxylation (SAD) route to the common building block 1,3-amino alcohol 9, from which (R)-norfluoxetine, (R)-fluoxetine and other rela
β¦ LIBER β¦
An asymmetric route to enantiomerically pure 1,2,3-trisubstituted cyclopropanes
β Scribed by Romo, Daniel; Meyers, A. I.
- Book ID
- 126982335
- Publisher
- American Chemical Society
- Year
- 1992
- Tongue
- English
- Weight
- 779 KB
- Volume
- 57
- Category
- Article
- ISSN
- 0022-3263
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