## Abstract The pathophysiological mechanisms underlying binge eating disorder (BED) are poorly understood. There is evidence that abnormalities in brain serotonin (5HT) play an important role in binge eating behavior, therefore genes involved in 5HT transmission, such as the 5HT transporter (5HTT)
β¦ LIBER β¦
An association study of a functional polymorphism of the serotonin transporter gene with personality and psychiatric symptoms
β Scribed by Jorm, A F; Henderson, A S; Jacomb, P A; Christensen, H; Korten, A E; Rodgers, B; Tan, X; Easteal, S
- Book ID
- 110058933
- Publisher
- Nature Publishing Group
- Year
- 1998
- Tongue
- English
- Weight
- 37 KB
- Volume
- 3
- Category
- Article
- ISSN
- 1359-4184
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## Abstract There is evidence that disturbances in central serotonin (5βHT) function have a role in impulsive aggression, violence, and criminality. A deletion/insertion polymorphism within the 5βHT transporter (5βHTT) promoter gene (5βHTT geneβlinked polymorphic region, 5βHTTLPR) is thought to be