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An association between glutathione S-transferase P1 gene polymorphism and younger age at onset of lung carcinoma

โœ Scribed by David P. Miller; Kofi Asomaning; Geoffrey Liu; John C. Wain; Thomas J. Lynch; Donna Neuberg; Li Su; David C. Christiani


Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
103 KB
Volume
107
Category
Article
ISSN
0008-543X

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Association between genetic polymorphism
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We examined the effect of genetic polymorphisms of phase-II enzymes, glutathione S-transferase P1 (GSTP1) and N-acetyltrans-ferase2 (NAT2) on susceptibility to esophageal squamous-cell carcinoma. To determine the genotypes of the 2 polymorphisms, PCR-based analysis was performed on samples from 66 J