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An Assessment of the Reaction Energetics for Cytochrome P450-Mediated Reactions

✍ Scribed by LeeAnn Higgins; Kenneth R. Korzekwa; Streedhara Rao; Magong Shou; Jeffrey P. Jones


Book ID
115568549
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
94 KB
Volume
385
Category
Article
ISSN
0003-9861

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## Abstract Cytochrome __b__~5~, a 17‐kDa hemeprotein associated primarily with the endoplasmic reticulum of eukaryotic cells, has long been known to augment some cytochrome P450 monooxygenase reactions, but the mechanism of stimulation has remained controversial. Studies in recent years have clari