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An archaebacteria-derived glutamyl-tRNA synthetase and tRNA pair for unnatural amino acid mutagenesis of proteins in Escherichia coli

✍ Scribed by Santoro, S. W.

Book ID
111873627
Publisher
Oxford University Press
Year
2003
Tongue
English
Weight
485 KB
Volume
31
Category
Article
ISSN
0305-1048

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Site-specific mutagenesis of DNA, developed some thirty years ago, has proven to be one of the most important advances in biology. By allowing the site-specific replacement of any amino acid in a protein with one of the other nineteen amino acids, it ushered in the new era of "Protein Engineering".