An approach to β-lactams from α,β-unsaturated sugar δ-lactones
✍ Scribed by Marek Chmielewski; Sylwester Maciejewski
- Book ID
- 107725597
- Publisher
- Elsevier Science
- Year
- 1986
- Tongue
- English
- Weight
- 173 KB
- Volume
- 157
- Category
- Article
- ISSN
- 0008-6215
No coin nor oath required. For personal study only.
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## Abstract The synthesis of six‐membered unsaturated δ‐lactones has generated considerable interest, due to their occurrence in a large number of natural products possessing potent biological activities. This microreview attempts to illustrate the different strategies used to obtain such compounds
γ-Oxo-α,β-unsaturated δ-lactones and lactams, which are in high yields, of the corresponding α-amino-γ-oxo-α,βunsaturated δ-lactones and -lactams, compounds of great easily accessible from their corresponding 2-furylcarbinols, were used as substrates for the 1,4-reductive addition of biological and