Synthetic Approaches to α,β-Unsaturated δ-Lactones and Lactols
✍ Scribed by Valérie Boucard; Garance Broustal; Jean Marc Campagne
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 265 KB
- Volume
- 2007
- Category
- Article
- ISSN
- 1434-193X
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✦ Synopsis
Abstract
The synthesis of six‐membered unsaturated δ‐lactones has generated considerable interest, due to their occurrence in a large number of natural products possessing potent biological activities. This microreview attempts to illustrate the different strategies used to obtain such compounds, with a special emphasis on catalytic and asymmetric approaches. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2007)
📜 SIMILAR VOLUMES
A series of 18 new a,&unsaturated &&&substituted &lactones was synthesized as possible therapeutic agents. The majority of the compounds described contain an aryloxy grou in the pposition of the lactone ring, while those naturally occurring in P+er mat&ticwn all contain an alkoxy group in this posit
γ-Oxo-α,β-unsaturated δ-lactones and lactams, which are in high yields, of the corresponding α-amino-γ-oxo-α,βunsaturated δ-lactones and -lactams, compounds of great easily accessible from their corresponding 2-furylcarbinols, were used as substrates for the 1,4-reductive addition of biological and
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