An Approach to the Synthesis of Novel Dihydroindoles Bearing Electron-Withdrawing Groups at C-2 Position
β Scribed by Maruoka, Hiroshi; Okabe, Fumi; Takasu, Masaru; Masumoto, Eiichi; Fujioka, Toshihiro; Yamagata, Kenji
- Book ID
- 125485705
- Publisher
- Japan Institute of Heterocyclic Chemistry
- Year
- 2014
- Tongue
- English
- Weight
- 716 KB
- Volume
- 88
- Category
- Article
- ISSN
- 0385-5414
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π SIMILAR VOLUMES
Dilute solutions of paclitaxel-related derivatives having chloroacetyl esters in the C2% position undergo ready methanolysis according to pseudo first-order kinetics while more concentrated solutions appear to be stabilized, possibly by the formation of hydrophobic aggregates that tend to bury this
The HPLC conditions associated with the retention times for the paclitaxel-related compounds listed in Table 1 should read as follows: RT=Retention times on an analytical HPLC (Waters) equipped with a reversed-phase column (Suplecosil C18) using gradient elution (60% acetonitrile in water going to 7