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An approach to the synthesis of ionophores related to A23187

✍ Scribed by Terry M. Cresp; Clive Ll. Probert; Franz Sondheimer


Publisher
Elsevier Science
Year
1978
Tongue
French
Weight
201 KB
Volume
19
Category
Article
ISSN
0040-4039

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πŸ“œ SIMILAR VOLUMES


Studies directed towards the total synth
✍ D.A. Evans; C.E. Sacks; R.A. Whitney; N.G. Mandel πŸ“‚ Article πŸ“… 1978 πŸ› Elsevier Science 🌐 French βš– 246 KB

The carboxylic acid antibiotic A-23187 (A) is a divalent cation ionophore which has been isolated from cultures of Streptomyces chartreusensis.' The structure and proposed absolute configuration2 have shown it to be one of a limited group of natural products, including oligomycin B3 and aplysiatoxin

The role of calcium in the acrosome reac
✍ Talbot, P. ;Summers, R. G. ;Hylander, B. L. ;Keough, E. M. ;Franklin, L. E. πŸ“‚ Article πŸ“… 1976 πŸ› John Wiley and Sons 🌐 English βš– 913 KB

## Abstract The role of Ca^+2^ in the acrosome reaction of echinoid and mammalian sperm was investigated using the Ca^+2^ transporting ionophore A23187. The ionophore induced morphologically normal acrosome reactions in both types of sperm (as assessed by electron microscopic observation of echinoi