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An Approach to Substituted 4-Hydroxypyran-2-ones: The Total Synthesis of Phenoxan

✍ Scribed by Garey, Donna; Ramirez, Mai-ly; Gonzales, Sam; Wertsching, Alan; Tith, Sovouthy; Keefe, Katie; Peña, Michael R.


Book ID
121426348
Publisher
American Chemical Society
Year
1996
Tongue
English
Weight
170 KB
Volume
61
Category
Article
ISSN
0022-3263

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A convenient synthesis of substituted 2-hydroxy-3-dimethylaminopropenoates is reported. They react with cyclic 1,3-diketones, with aromatic and heteroaromatic hydroxy compounds to afford the corresponding 3-substituted hydroxytetrahydro-2H-l-benzopyran-2-ones, benzo-and naphthopyran-2-ones and azolo