An approach for high-throughput structure determination of proteins by NMR spectroscopy
β Scribed by Ales Medek; Edward T. Olejniczak; Robert P. Meadows; Stephen W. Fesik
- Book ID
- 111564663
- Publisher
- Springer Netherlands
- Year
- 2000
- Tongue
- English
- Weight
- 177 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0925-2738
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## Abstract The paper briefly reviews the process of determining the structures of membrane proteins by NMR spectroscopy of aligned samples, describes the integration of recent developments in the interpretation of spectra of aligned proteins and illustrates the application of these methods to the
Dedicated to Professor Horst Kessler on the occasion of his 70th birthday and to Professor Christian Griesinger on the occasion of his 50th birthday Eukaryotic proteins typically have a modular architecture, characterized by multiple structural domains that are connected by flexible linkers. Regulat