✦ LIBER ✦

An apparent lack of association between Helicobacter pylori infection and risk of gastric cancer in China

✍ Scribed by Penelope M. Webb; Mimi C. Yu; David Forman; Brian E. Henderson; Diane G. Newell; Jian-Min Yuan; Yu-Tang Gao; Ronald K. Ross

Publisher: John Wiley and Sons
Year: 1996
Tongue: French
Weight: 566 KB
Volume: 67
Category: Article
ISSN: 0020-7136
DOI: 10.1002/(sici)1097-0215(19960904)67:5<603::aid-ijc2>3.0.co;2-y

No coin nor oath required. For personal study only.

✦ Synopsis

Several prospective studies have shown a significant association between Helicobacter pylori seropositivity and the risk of gastric cancer. Only a small proportion of H. pylori-infected individuals will, however, develop gastric cancer, and it is unclear what effects other factors, such as diet, might have on the risk of cancer. Eighty-seven subjects with gastric cancer were identified during the first 6 years of follow-up (mean 2.4 years) of a cohort of middle-aged men from Shanghai, China. They were matched with 261 cancer-free controls, and serum samples from all subjects, obtained at recruitment, were assayed for anti-H. pylori IgG antibodies. Questionnaire data provided information on a wide range of socio-demographic life-style and dietary variables. H. pylori seropositivity rates

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