An amperometric microsensor array with 1024 individually addressable elements for two-dimensional concentration mapping

✍ Scribed by T. Hermes; M. Bühner; S. Bücher; C. Sundermeier; C. Dumschat; M. Borchardt; K. Cammann; M. Knoll

• Publisher: Elsevier Science
• Year: 1994
• Tongue: English
• Weight: 616 KB
• Volume: 21
• Category: Article
• ISSN: 0925-4005
• DOI: 10.1016/0925-4005(93)01209-m

✦ Synopsis

A microsensor array with 32 rows and 32 columns of 1024 individual addressable amperometric cells on a 30 mm X30 mm Si substrate has been developed. The performance of the two-dimensional measuring system is described with an example of a Clark-type oxygen-measurement system, leading to a novel nearly real-time oxygen-concentration mapping important for transplantation medicine and biosensor applications. Special attention has been paid to an easy, reliable mass-production process with integrated electrolyte and membrane immobilization, resulting in low-cost devices. Parameters influencing the measurements can be chosen by a specially developed software that allows nearly real-time amperometric measurements to be realized after an automated calibration of the whole array. As a sub-sensor for biosensors based on oxygen consumption or hydrogen peroxide production, exciting new possibilities for two-dimensional concentration mapping of many other analytes open new horizons in analytical chemistry.