An alternative synthesis of 4-deoxy-4-fluoro-d-glucose and its transport in the human erythrocyte
✍ Scribed by Diago Philip Lopes; Norman Fletcher Taylor
- Book ID
- 108308750
- Publisher
- Elsevier Science
- Year
- 1979
- Tongue
- English
- Weight
- 739 KB
- Volume
- 73
- Category
- Article
- ISSN
- 0008-6215
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Elucidation of the mechanism of facilitated D‐glucose transport in human erythrocytes is dependent on the identification and isolation of the membrane protein(s) mediating this process. Based on the fact that stereospecific D‐glucose transport is reconstituted in liposomes prepared by s
## Abstract The homologous compounds of the 4‐alkoxy‐ and 4‐alkylamino‐series inhibit the exchange transport of glucose in human erythrocytes; they show a competitive inhibition with one or two inhibitor molecules which become bound to a singular site of the transport system for glucose. The import
## Abstract 1‐(2‐Deoxy‐2‐fluoro‐4‐thio‐β‐D‐arabinofuranosyl) cytosine (4′‐thio‐FAC) is a deoxycytidine analog that has been shown previously to have impressive anti‐proliferative and cytotoxic effects __in vitro__ and __in vivo__ toward colorectal and gastric tumors. In our present studies, the pha
Treatment of 3-0-acetyl-5-deoxy-5-(dimethoxyphosphinyl)-l,2-O-isopropylidene-cr-D-glucofuranose (7) with dihydropyran in the presence of pyridinium ptoluenesulfonate gave the 6-0-(tetrahydropyran-2-yl) derivative in 91% yield. Ring-enlargement of this compound by the known, 2-step procedure gave 5-d