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The effect of homologous localanesthetics of the 4-alkoxy- and 4-alkylamino-benzoicacid-diethylamino-ethylester-hydrochloride-series on the glucose transport in human erythrocytes

✍ Scribed by L. Lacko; B. Wittke; I. Lacko


Publisher
John Wiley and Sons
Year
1979
Tongue
English
Weight
373 KB
Volume
100
Category
Article
ISSN
0021-9541

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✦ Synopsis


Abstract

The homologous compounds of the 4‐alkoxy‐ and 4‐alkylamino‐series inhibit the exchange transport of glucose in human erythrocytes; they show a competitive inhibition with one or two inhibitor molecules which become bound to a singular site of the transport system for glucose. The importance of length of hydrocarbon chain of the localanesthetics for the mode of their action is discussed.