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An allylic isoprenoid C5 nucleophile for the synthesis of forskolin

✍ Scribed by Dirk Behnke; Stefan Hamm; Lothar Hennig; Peter Welzel

Publisher
Elsevier Science
Year
1997
Tongue
French
Weight
189 KB
Volume
38
Category
Article
ISSN
0040-4039

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✦ Synopsis

InCIrmediated couplin 8 of6-alkoxy allyllc stannane 9b with aldehydes has been shown to give the co-coupling products in high yield, probably via two S~' processes. Most specifically, drimenai (rac-l) has been convened into labdane derivative 17 which is considered to be an important intermediate on the way to forskolin.

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