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An algorithm to approximate the likelihood for pedigree data with loops by cutting

โœ Scribed by C. Stricker; R. L. Fernando; R. C. Elston

Book ID
104670925
Publisher
Springer
Year
1995
Tongue
English
Weight
1014 KB
Volume
91-91
Category
Article
ISSN
0040-5752

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An efficient algorithm to compute the po
An efficient algorithm to compute the posterior genotypic distribution for every member of a pedigree without loops
โœ R. L. Fernando; C. Stricker; R. C. Elston ๐Ÿ“‚ Article ๐Ÿ“… 1993 ๐Ÿ› Springer ๐ŸŒ English โš– 450 KB

This paper describes a non-iterative, recursive method to compute the likelihood for a pedigree without loops, and hence an efficient way to compute genotype probabilities for every member of the pedigree. The method can be used with multiple mates and large sibships. Scaling is used in calculations