AN 125I-LABELED N6-SUBSTITUTED AZIDO ANALOG OF NAD+ FOR THE PHOTOAFFINITY LABELING OF NAD+-LINKED ENZYMES

Synthesis of a 125I labelled azido-subst

Synthesis of a 125I labelled azido-substituted glibenclamide analogue for photoaffinity labelling of the sulfonylurea receptor

✍ Franz Chudziak; Mathias Schwanstecher; Hartmut Laatsch; Uwe Panten 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 French ⚖ 286 KB

## Abstract N‐{4‐(2‐{4‐Azido‐2‐hydroxy‐5‐[^125^I]iodobenzamido}ethyl)benzenesul]‐N′‐cyclohexylurea has been prepared as a novel photoaffinity ligand for the sulfonylurea receptor. This involved synthesis of a 4‐azidosalicyloyl analogue of glibenclamide and treatment of the analogue with Na^125^I an