Intracellular trafficking of the Ξ²-secre
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Pei Zhi; Cheryl Chia; Paul A. Gleeson
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Article
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2011
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John Wiley and Sons
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English
β 354 KB
The main component of the amyloid plaques found in the brains of those with Alzheimer's disease (AD) is a polymerized form of the b-amyloid peptide (Ab) and is considered to play a central role in the pathogenesis of this neurodegenerative disorder. Ab is derived from the proteolytic processing of t