The family of calcium-activated neutral proteases, calpains, appears to play a key role in neuropathologic events following traumatic brain injury (TBI). Neuronal calpain activation has been observed within minutes to hours after either contusive or diffuse brain trauma in animals, suggesting that c
β¦ LIBER β¦
Amyloid precursor protein secretases as therapeutic targets for traumatic brain injury
β Scribed by Loane, David J; Pocivavsek, Ana; Moussa, Charbel E-H; Thompson, Rachel; Matsuoka, Yasuji; Faden, Alan I; Rebeck, G William; Burns, Mark P
- Book ID
- 109926170
- Publisher
- Nature Publishing Group
- Year
- 2009
- Tongue
- English
- Weight
- 362 KB
- Volume
- 15
- Category
- Article
- ISSN
- 1078-8956
- DOI
- 10.1038/nm.1940
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