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Amyloid precursor protein proteoglycan is increased after brain damage

✍ Scribed by Olga Salinero; Juan Jose Garrido; Francisco Wandosell


Book ID
117618295
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
473 KB
Volume
1406
Category
Article
ISSN
0925-4439

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Progressive cerebral deposition of ␀-amyloid peptide either in blood vessels or around neurites is one of the most important features of Alzheimer's disease (AD). The ␀-peptide, known as A␀ or A4, is produced by proteolytic cleavage of the amyloid precursor protein (APP). Two APP processing pathways